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Catalog No: ATM00001
Size:100ug
Price: $499.00
SKU
ATM00001
Availability: Domestic: 3-5 business days International: 3-5 business days
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Datasheets/ManualsPrintable datasheet for FTO Recombinant Antibody [8M13] (ATM00001)
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatPBS w/ 0.09% sodium azide
ClonalityRecombinant Monoclonal
Clone8M13
IsotypeIgG
HostRabbit
ApplicationIF, WB
Additional InformationThis product was developed using Active Motif’s AbFlex® antibody technology.
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenRecombinant Human FTO aa328-505
PurificationProtein A
Concentration1 mg/mL
Gene SymbolFTO
Gene Full Namealpha-ketoglutarate-dependent dioxygenase
Alias SymbolsFTO
NCBI Gene Id79068
Protein NameAlpha-ketoglutarate-dependent dioxygenase FTO
Description of TargetRNA demethylase that mediates oxidative demethylation of different RNA species, such as mRNAs, tRNAs and snRNAs, and acts as a regulator of fat mass, adipogenesis and energy homeostasis (PubMed:22002720, PubMed:26458103, PubMed:28002401, PubMed:30197295, PubMed:26457839, PubMed:25452335). Specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:22002720, PubMed:26458103, PubMed:30197295, PubMed:26457839, PubMed:25452335), among other targets.
Uniprot IDQ9C0B1-1
Protein Size (# AA)505
Molecular Weight58.3 kDa
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