FOXP3 Antibody (OAAD00447)

Catalog No: OAAD00447

Size:0.1 mg

western blot analysis of truncated Foxp3 recombinant protein with Foxp3 antibody.

Product Info

• Predicted Species Reactivity: Mouse
• Product Format: Liquid
• Clonality: Monoclonal
• Clone: 6H3C5H3
• Isotype: IgG2b
• Host: Mouse
• Application: WB, FC
• Reconstitution and Storage: Stored at -20C
• Immunogen: Ni-NTA purified truncated recombinant Foxp3 expressed in E. Coli strain BL21 (DE3)
• Purification: Antibodies are purified by protein A affinity chromatography
• Concentration: 1 mg/ml
• Application Info: WB 1:200 - 1:1000
  FC 1:100 - 1:500
  ELISA Propose dilution 1:10,000
  Determining optimal working dilutions by titration test.
• Reference: 1 Roncador G et al. Eur J Immunol, 2005, 35:1681- 1691 .
  2 Yisong YW, PNAS, 2005 102(14):5126-5131.

Target Info

• Gene Symbol: Foxp3
• Alias Symbols: sf, JM2, scu, scurfin
• NCBI Gene Id: 20371
• Protein Name: Forkhead box protein P3
• Description of Target: The transcription factor Foxp family included Foxp1, Foxp2, and Foxp3. The Foxp3(50KDa)played a key role in CD4(+) CD25(+) regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little was known about the frequency of CD4(+)CD25(+) cells that express FOXP3 protein nor the distribution of these cells in vivo. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
• Uniprot ID: Q99JB6