FOXP3 Antibody - C-terminal region (OAAB01500)

Catalog#: OAAB01500

• Size: 400ul

• Gene Symbol: FOXP3
• NCBI Gene Id: 50943
• Protein Name: Forkhead box protein P3
• Swissprot Id: Q9BZS1
• Protein Accession #: NP_001107849.1
• Alias Symbols: Scurfin, Forkhead box protein P3, FOXP3, IPEX,
• Replacement Item: This antibody may replace item sc-130666 from Santa Cruz Biotechnology.
• Description of Target: FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in FOXP3 gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
• Molecular Weight: 47244 Da
• Host: Rabbit
• Clonality: Polyclonal
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Application: WB, IHC-P, FC
• RNA Seq: Find tissues and cell lines supported by RNA-seq analysis to express FOXP3.
• Immunogen: This FOXP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human FOXP3.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Monkey
• Product Format: Liquid. PBS with 0.09% (W/V) sodium azide.
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Isotype: Rabbit Ig
• Application Info: WB 1:1000
  IHC-P 1:10~50
  FC 1:10~50
  
  Function: Probable transcription factor. Plays a critical role in the control of immune response.
  Cellular Location: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089}
• Publications:

  Yoon, SO; Kim, EK; Lee, M; Jung, WY; Lee, H; Kang, Y; Jang, YJ; Hong, SW; Choi, SH; Yang, WI; NOVA1 inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal. 7, 2475-95 (2016). WB, IHC-P, FC, Human, Mouse 26673617

Protocol:

Tips Information:

Product Protocol: FOXP3 antibody tested with human, mouse 293, Jurkat and mouse liver by western blot (OAAB01500)

Product Protocol: FOXP3 antibody tested with human lymph in immunohistochemistry (IHC) (OAAB01500)