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FOXP3 Antibody - C-terminal region (OAAB01500)

400ul
$390.00
In Stock
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Predicted Species Reactivity:
Human, Mouse
Product Format:
Liquid. PBS with 0.09% (W/V) sodium azide.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Host:
Rabbit
Application:
WB, IHC-P, FC
:::
Function: Probable transcription factor. Plays a critical role in the control of immune response.
Cellular Location: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089}
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
FOXP3
NCBI Gene Id:
50943
Protein Name:
Forkhead box protein P3
Swissprot Id:
Q9BZS1
Protein Accession #:
NP_001107849.1
Alias Symbols:
Scurfin, Forkhead box protein P3, FOXP3, IPEX,
Replacement Item:
This antibody may replace item sc-130666 from Santa Cruz Biotechnology.
Description of Target:
FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in FOXP3 gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
Molecular Weight:
47244 Da
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express FOXP3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express FOXP3.
Immunogen:
This FOXP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human FOXP3.
Predicted Homology Based on Immunogen Sequence:
Human; Mouse; Monkey
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals:
Printable datasheet for anti-FOXP3 antibody - OAAB01500
Application Info:
WB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50
Publications:

Yoon, SO; Kim, EK; Lee, M; Jung, WY; Lee, H; Kang, Y; Jang, YJ; Hong, SW; Choi, SH; Yang, WI; NOVA1 inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal. 7, 2475-95 (2016). WB, IHC-P, FC, Human, Mouse 26673617

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