- Gene Symbol:
- FOXP3
- NCBI Gene Id:
- 50943
- Protein Name:
- Forkhead box protein P3
- Swissprot Id:
- Q9BZS1
- Protein Accession #:
- NP_001107849.1
- Alias Symbols:
- Scurfin, Forkhead box protein P3, FOXP3, IPEX,
- Replacement Item:
- This antibody may replace item sc-130666 from Santa Cruz Biotechnology.
- Description of Target:
- FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in FOXP3 gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
- Molecular Weight:
- 47244 Da
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Purification:
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Application:
- WB, IHC-P, FC
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express FOXP3.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express FOXP3.
- Immunogen:
- This FOXP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human FOXP3.
- Predicted Homology Based on Immunogen Sequence:
- Human; Mouse; Monkey
- Product Format:
- Liquid. PBS with 0.09% (W/V) sodium azide.
- Reconstitution and Storage:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Concentration:
- Approximately 0.5mg/ml. Actual concentration varies with each lot.
- Datasheets/Manuals:
- Printable datasheet for anti-FOXP3 antibody - OAAB01500
- Isotype:
- Rabbit Ig
- Application Info:
- WB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50 - :::
- Function: Probable transcription factor. Plays a critical role in the control of immune response.
Cellular Location: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089} - Publications:
Yoon, SO; Kim, EK; Lee, M; Jung, WY; Lee, H; Kang, Y; Jang, YJ; Hong, SW; Choi, SH; Yang, WI; NOVA1 inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal. 7, 2475-95 (2016). WB, IHC-P, FC, Human, Mouse 26673617
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