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FOXP1 Antibody (OACA02421)

100 ug
$315.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB, IHC, CHIP
Reconstitution and Storage:
Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement Item:
This antibody may replace item sc-31731 from Santa Cruz Biotechnology.
Immunogen:
Recombinant human Forkhead box protein P1 protein
Purification:
Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence:
Human
Datasheets/Manuals:
Printable datasheet for anti-FOXP1 (OACA02421) antibody
Specificity:
Human
Formulation:
Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference:
[1] Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III J. Proteome Res. 7:1346-1351 (2008).
[2] De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment. Hamdan F.F., Daoud H., Rochefort D., Piton A., Gauthier J., Langlois M., Foomani G., Dobrzeniecka S., Krebs M.O., Joober R., Lafreniere R.G., Lacaille J.C., Mottron L., Drapeau P., Beauchamp M.H., Phillips M.S., Fombonne E., Rouleau G.A., Michaud J.L.Am. J. Hum. Genet. 87:671-678 (2010).
[3] An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Gabut M., Samavarchi-Tehrani P., Wang X., Slobodeniuc V., O'Hanlon D., Sung H.K., Alvarez M., Talukder S., Pan Q., Mazzoni E.O., Nedelec S., Wichterle H., Woltjen K., Hughes T.R., Zandstra P.W., Nagy A., Wrana J.L., Blencowe B.J.Cell 147:132-146 (2011).
Gene Symbol:
FOXP1
Official Gene Full Name:
forkhead box P1
Alias Symbols:
MFH, QRF1, 12CC4, hFKH1B, HSPC215
NCBI Gene Id:
27086
Protein Name:
forkhead box protein P1
Description of Target:
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.
Swissprot Id:
Q9H334
Protein Accession #:
NP_001012523.1
Nucleotide Accession #:
NM_001012505.1
Protein Size (# AA):
677
Molecular Weight:
75 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express FOXP1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express FOXP1.

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