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FOXA3 antibody - middle region (ARP31945_P050)

100 ul
$319.00
In Stock
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Conjugation Options

ARP31945_P050-FITC Conjugated

ARP31945_P050-HRP Conjugated

ARP31945_P050-Biotin Conjugated

Gene Symbol:
FOXA3
NCBI Gene Id:
3171
Official Gene Full Name:
Forkhead box A3
Protein Name:
Hepatocyte nuclear factor 3-gamma
Swissprot Id:
P55318
Protein Accession #:
NP_004488
Nucleotide Accession #:
NM_004497
Alias Symbols:
FKHH3, HNF3G, TCF3G
Replacement Item:
This antibody may replace item sc-111854 from Santa Cruz Biotechnology.
Description of Target:
FOXA3 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved.
Protein Size (# AA):
350
Molecular Weight:
37kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express FOXA3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express FOXA3.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human FOXA3
Tested Species Reactivity:
Human, Mouse
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 85%; Rat: 100%; Zebrafish: 79%
Complete computational species homology data:
Anti-FOXA3 (ARP31945_P050)
Peptide Sequence:
Synthetic peptide located within the following region: FENGCYLRRQKRFKLEEKVKKGGSGAATTTRNGTGSAASTTTPAATVTSP
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
PPARA; ALX4; TLE2; TLE1; HMGB1;
Blocking Peptide:
For anti-FOXA3 (ARP31945_P050) antibody is Catalog # AAP31945 (Previous Catalog # AAPP03641)
Datasheets/Manuals:
Printable datasheet for anti-FOXA3 (ARP31945_P050) antibody
Target Reference:
Kaestner,K.H. et al., (2000) Trends Endocrinol. Metab. 11 (7), 281-285
Publications:

Menga, A. et al. Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier. Eur. Neuropsychopharmacol. 23, 978-87 (2013). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 22959654

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