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Foxa2 Antibody - middle region (ARP37060_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP37060_P050-FITC Conjugated

ARP37060_P050-HRP Conjugated

ARP37060_P050-Biotin Conjugated

Gene Symbol:
Foxa2
Official Gene Full Name:
Forkhead box A2
NCBI Gene Id:
15376
Protein Name:
Hepatocyte nuclear factor 3-beta
Swissprot Id:
P35583
Protein Accession #:
NP_034576
Nucleotide Accession #:
NM_010446
Alias Symbols:
HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b
Replacement Item:
This antibody may replace item sc-101060 from Santa Cruz Biotechnology.
Description of Target:
Foxa2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.Foxa2 is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.Foxa2 binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development Foxa2 is required for notochord formation.Foxa2 is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs.
Protein Size (# AA):
459
Molecular Weight:
48
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express Foxa2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express Foxa2.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of mouse Foxa2
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Tested Species Reactivity:
Mouse
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 86%; Rat: 100%
Complete computational species homology data:
Anti-Foxa2 (ARP37060_P050)
Peptide Sequence:
Synthetic peptide located within the following region: SSGGKKTAPGSQASQAQLGEAAGSASETPAGTESPHSSASPCQEHKRGGL
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
Ucp2; Gck; Pklr; Hnf4a; Igfbp1; Acadm; Acadvl;
Blocking Peptide:
For anti-Foxa2 (ARP37060_P050) antibody is Catalog # AAP37060 (Previous Catalog # AAPP09254)
Datasheets/Manuals:
Printable datasheet for anti-Foxa2 (ARP37060_P050) antibody

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