Size:100 ul
Special Price $229.00 Regular Price $289.00
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ARP37060_P050
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Conjugation Options

ARP37060_P050-FITC Conjugated

ARP37060_P050-HRP Conjugated

ARP37060_P050-Biotin Conjugated

Foxa2 Antibody - middle region (ARP37060_P050)

Catalog#: ARP37060_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Mouse
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-101060 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of mouse Foxa2
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 86%; Rat: 100%
Complete computational species homology data Anti-Foxa2 (ARP37060_P050)
Peptide Sequence Synthetic peptide located within the following region: SSGGKKTAPGSQASQAQLGEAAGSASETPAGTESPHSSASPCQEHKRGGL
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-Foxa2 (ARP37060_P050) antibody is Catalog # AAP37060 (Previous Catalog # AAPP09254)
Datasheets/Manuals Printable datasheet for anti-Foxa2 (ARP37060_P050) antibody
Gene Symbol Foxa2
Official Gene Full Name Forkhead box A2
Alias Symbols HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b
NCBI Gene Id 15376
Protein Name Hepatocyte nuclear factor 3-beta
Description of Target Foxa2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.Foxa2 is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.Foxa2 binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development Foxa2 is required for notochord formation.Foxa2 is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs.
Swissprot Id P35583
Protein Accession # NP_034576
Nucleotide Accession # NM_010446
Protein Size (# AA) 459
Molecular Weight 48
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express Foxa2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express Foxa2.
Protein Interactions Ucp2; Gck; Pklr; Hnf4a; Igfbp1; Acadm; Acadvl;
  1. What is the species homology for "Foxa2 Antibody - middle region (ARP37060_P050)"?

    The tested species reactivity for this item is "Mouse". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat".

  2. How long will it take to receive "Foxa2 Antibody - middle region (ARP37060_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "Foxa2 Antibody - middle region (ARP37060_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Foxa2 Antibody - middle region (ARP37060_P050)"?

    This target may also be called "HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b" in publications.

  5. What is the shipping cost for "Foxa2 Antibody - middle region (ARP37060_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Foxa2 Antibody - middle region (ARP37060_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Foxa2 Antibody - middle region (ARP37060_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "48".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Foxa2 Antibody - middle region (ARP37060_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "FOXA2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "FOXA2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "FOXA2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "FOXA2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "FOXA2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "FOXA2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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