Size:100 ul
Special Price $229.00 Regular Price $289.00
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ARP31944_P050
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Conjugation Options

ARP31944_P050-FITC Conjugated

ARP31944_P050-HRP Conjugated

ARP31944_P050-Biotin Conjugated

FOXA2 Antibody - middle region (ARP31944_P050)

Catalog#: ARP31944_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-101060 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FOXA2
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Dog: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 77%; Rat: 92%
Complete computational species homology data Anti-FOXA2 (ARP31944_P050)
Peptide Sequence Synthetic peptide located within the following region: ASQAQLGEAAGPASETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALS
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-FOXA2 (ARP31944_P050) antibody is Catalog # AAP31944 (Previous Catalog # AAPP02841)
Datasheets/Manuals Printable datasheet for anti-FOXA2 (ARP31944_P050) antibody
Sample Type Confirmation

FOXA2 is strongly supported by BioGPS gene expression data to be expressed in 721_B, HepG2

Target Reference Yang,G., (2008) Blood 111 (1), 392-401
Publications

Kallas, A., Pook, M., Trei, A. & Maimets, T. SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate. Stem Cells Int. 2014, 298163 (2014). WB, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat 24707296

Menga, A. et al. Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier. Eur. Neuropsychopharmacol. 23, 978-87 (2013). WB, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat 22959654

Richards, T. J. et al. Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis. Am. J. Physiol. Lung Cell. Mol. Physiol. 302, L746-54 (2012). WB, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat 22268124

Gene Symbol FOXA2
Official Gene Full Name Forkhead box A2
Alias Symbols HNF3B, MGC19807, TCF3B
NCBI Gene Id 3170
Protein Name Hepatocyte nuclear factor 3-beta
Description of Target FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene. This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.
Swissprot Id Q9Y261
Protein Accession # NP_068556
Nucleotide Accession # NM_021784
Protein Size (# AA) 457
Molecular Weight 48kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express FOXA2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express FOXA2.
Protein Interactions PPARGC1B; GSC; EN2; OTX2; ONECUT1; NCOA1; TLE1; MIP; HOXA5; LHX1;
  1. What is the species homology for "FOXA2 Antibody - middle region (ARP31944_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Dog, Horse, Human, Mouse, Pig, Rabbit, Rat".

  2. How long will it take to receive "FOXA2 Antibody - middle region (ARP31944_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "FOXA2 Antibody - middle region (ARP31944_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "FOXA2 Antibody - middle region (ARP31944_P050)"?

    This target may also be called "HNF3B, MGC19807, TCF3B" in publications.

  5. What is the shipping cost for "FOXA2 Antibody - middle region (ARP31944_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "FOXA2 Antibody - middle region (ARP31944_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "FOXA2 Antibody - middle region (ARP31944_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "48kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "FOXA2 Antibody - middle region (ARP31944_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "FOXA2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "FOXA2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "FOXA2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "FOXA2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "FOXA2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "FOXA2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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