FMR1 Antibody (OAEC04490)

Catalog No: OAEC04490

Size:100 ug/100 ul

Western blot analysis using FMR1 mouse mAb against Jurkat (1) and K562 (2) cell lysate.

Immunohistochemical analysis of paraffin-embedded human brain tissues, showing cytoplasmic localization with DAB staining using FMR1 mouse mAb.

Immunofluorescence analysis of NIH/3T3 cells using FMR1 mouse mAb (green). Blue. DRAQ5 fluorescent DNA dye. Red. Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Ascitic fluid containing 0.03% sodium azide
• Clonality: Monoclonal
• Clone: 4G9
• Isotype: IgG1
• Host: Mouse
• Application: WB, IHC, IF
• Reconstitution and Storage: Store at 4C, for long term storage, store at -20C.
• Immunogen: Purified recombinant fragment of human FMR1 expres sed in EColi.
• Concentration: 1 mg/ml
• Application Info: WB: 1/500 - 1/2000
  IHC: 1/200 - 1/1000
  IF: 1/200 - 1/1000
  ELISA: 1/10000
  

Target Info

• Gene Symbol: FMR1
• Gene Full Name: fragile X mental retardation 1
• Alias Symbols: POF, FMRP, POF1, FRAXA
• NCBI Gene Id: 2332
• Description of Target: FMR1, also known as POF, FMRP, FRAXA. Entrez Protein. NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular R NA transport and in the regulation of translation of target mRNAs .
• Uniprot ID: Q06787
• Molecular Weight: 71 kDa