Flt3 Ligand Protein (OPPA00603)

Catalog No: OPPA00603 (Formerly GWB-C69CF7)

Size:2UG

Product Info

• Predicted Species Reactivity: Mouse
• Product Format: The protein was lyophilized with no additives. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• Host: E. Coli
• Additional Information: Solubility: It is recommended to reconstitute the lyophilized Flt3-Ligand in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
  Biological Activity: The activity is determined by the ability to generate CD11c+ splenic dendritic cells in vivo in C57B1/6-12 week female mice. To obtain the desired affect, mice were treated with approximately 25ug of flt3-ligand once daily for 9 consecutive days via intraperitoneal injection.
  Product Introduction: FLT3 ligand is a receptor for the fl cytokine has a tyrosine-protein kinase activity & a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation.
  Product Description: Flt3-Ligand Mouse Recombinant produced in E.Coli is non-glycosylated, polypeptide chain containing 144 amino acids and having a molecular mass of 16431 Dalton. Flt3-Ligand is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: Lyophilized Flt3-Ligand although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Flt-3 Ligand should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
• Purity: Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Peptide Sequence: The sequence of the first five N - terminal amino acids was determined and was found to be Thr - Gln - Asp - Cys - Ser.

Target Info

• Gene Symbol: mFlt3 Ligand
• Alias Symbols: Ly72L, Flt3lg
• NCBI Gene Id: 14256
• Protein Name: Fms-related tyrosine kinase 3 ligand
• Description of Target: Recombinant Mouse Flt3-Ligand
• Uniprot ID: P49772
• Protein Accession #: NP_038548.3
• Protein Size (# AA): Recombinant