FIM2 Recombinant Protein (Bordetella pertussis) (OPCA03999)

Catalog No: OPCA03999

Product Info

• Predicted Species Reactivity: Bordetella pertussis
• Product Format: Liquid or Lyophilized powder
• Additional Information: Species Specificity Detail: Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
• Reconstitution and Storage: -20°C or -80°C
• Purification: Affinity purified using IMAC
• Purity: Greater than 90% as determined by SDS-PAGE.
• Peptide Sequence: DDGTIVITGTITDTTCVIEDPSGPNHTKVVQLPKISKNALKANGDQAGRTPFIIKLKDCPSSLGNGVKAYFEPGPTTDYSTGDLRAYKMVYATNPQTQLSNITAATEAQGVQVRISNLNDSKITMGANEATQQAAGFDPEVQTGGTSRTVTMRYLASYVKKNGDVEASAITTYVGFSVVYP
• Protein Sequence: Full Length of Mature Protein: DDGTIVITGTITDTTCVIEDPSGPNHTKVVQLPKISKNALKANGDQAGRTPFIIKLKDCPSSLGNGVKAYFEPGPTTDYSTGDLRAYKMVYATNPQTQLSNITAATEAQGVQVRISNLNDSKITMGANEATQQAAGFDPEVQTGGTSRTVTMRYLASYVKKNGDVEASAITTYVGFSVVYP
• Source: E.coli
• Protein Range: 27-207 aa
• Tag: N-terminal 6xHis-tagged
• Reference: Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.Nat. Genet. 35:32-40(2003)

Target Info

• Gene Symbol: BP_RS05570
• Gene Full Name: fimbrial protein
• Alias Symbols: BP_RS05570;BP1119;fimbrial protein.
• NCBI Gene Id: 2665370
• Protein Name: Serotype 2 fimbrial subunit
• Description of Target: Bordetella pertussis is the causative agent of whooping cough. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms. It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B.pertussis are prime candidates for being involved in this process.
• Uniprot ID: P05788
• Protein Accession #: NP_879898
• Nucleotide Accession #: NC_002929
• Protein Size (# AA): Recombinant
• Molecular Weight: 23.2 kDa