FibrinoPeptide B (KLH - Conjugated) (OOCD00278)

Catalog No: OOCD00278

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Conjugation: KLH
• Application: Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: PubChem: FPB
  Residues: Gln31-Arg44
  Chemical Formula: C8H18N4O2
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Purity: > 90%
• Formulation: PBS, pH7.4.
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: FGB
• Gene Full Name: fibrinogen beta chain
• Alias Symbols: beta-fibrinogen;epididymis secretory sperm binding protein Li 78p;fibrinogen beta chain;fibrinogen, B beta polypeptide;HEL-S-78p.
• NCBI Gene Id: 2244
• Protein Name: Fibrinogen beta chain
• Description of Target: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
• Uniprot ID: P02675
• Protein Size (# AA): Gln31~Arg44
• Molecular Weight: 202.3 Da