FHIT Protein (OPPA02301)

Catalog No: OPPA02301 (Formerly GWB-BSP480)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid 20mM Tris-HCl (pH 8) & 10% glycerol
  Physical Appearance: Sterile filtered colorless solution
• Host: E. Coli
• Reconstitution and Storage: Store at 4C if entire vial will be used within 2-4 weeks. Store frozen at -20C for longer periods of time. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
• Purification: Purified by standard chromatography
• Concentration: 1 mg/ml
• Purity: Greater than 95% as determined by SDS-PAGE.
• Peptide Sequence: MSFRFGQHLI KPSVVFLKTE LSFALVNRKP VVPGHVLVCP LRPVERFHDL RPDEVADLFQ TTQRVGTVVE KHFHGTSLTF SMQDGPEAGQ TVKHVHVHVL PRKAGDFHRN DSIYEELQKH DKEDFPASWR SEEEMAAEAA ALRVYFQLEH HHHHH.
• Tag: C-terminal His Tag

Target Info

• Gene Symbol: FHIT
• Alias Symbols: FRA3B, AP3Aase
• NCBI Gene Id: 2272
• Protein Name: Bis(5'-adenosyl)-triphosphatase
• Description of Target: FHIT enzyme cleaves adenosine 5'' PPP 5'' A to yield AMP and ADP. FHIT gene includees the regular fragile site FRA3B on chromosome 3. Alterations and deletions of the FHIT gene are highly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT functions as a tumor suppressor and physically relates with ubiquitin conjugating enzyme 9. FHIT Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 155 amino acids (1-147 a.a.).
• Uniprot ID: P49789
• Protein Accession #: NP_001159715.1
• Protein Size (# AA): Recombinant
• Molecular Weight: 18 kDa