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Catalog No: OAAN00708
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OAAN00708
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FGFR2 Antibody (OAAN00708)

Datasheets/ManualsPrintable datasheet for anti-FGFR2 (OAAN00708)
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationWB, IHC, IF
Additional InformationPositive samples: 293T, LO2
Cellular location: Cell membrane, Cytoplasmic vesicle, Golgi apparatus, Secreted, Single-pass type I membrane protein
Reconstitution and StorageStore at -20°C. Avoid repeated freeze/thaw cycles.
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGFR2 (NP_000132.3).
PurificationAffinity purified
Peptide SequenceMVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPR
ConcentrationVaries by lot. See vial for exact concentration.
Application InfoWB: 1:500 - 1:2,000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
Optimal dilutions should be determined by the end user.
Gene SymbolFGFR2
Gene Full Namefibroblast growth factor receptor 2
Alias SymbolsBEK, JWS, BBDS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM
NCBI Gene Id2263
Protein NameFibroblast growth factor receptor 2
Description of TargetThe protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Uniprot IDP21802
Protein Accession #NP_000132.3
Nucleotide Accession #NM_000141.4
Molecular Weight110 kDa
  1. What is the species homology for "FGFR2 Antibody (OAAN00708)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "FGFR2 Antibody (OAAN00708)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "FGFR2 Antibody (OAAN00708)" provided in?

    This item is provided in "Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH 7.3".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "FGFR2 Antibody (OAAN00708)"?

    This target may also be called "BEK, JWS, BBDS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM" in publications.

  5. What is the shipping cost for "FGFR2 Antibody (OAAN00708)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "FGFR2 Antibody (OAAN00708)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "FGFR2 Antibody (OAAN00708)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "110 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "FGFR2 Antibody (OAAN00708)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "FGFR2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "FGFR2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "FGFR2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "FGFR2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "FGFR2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "FGFR2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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