Catalog No: ARP53669_P050
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ARP53669_P050
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FGFR1OP Antibody - N-terminal region (ARP53669_P050)

Datasheets/ManualsPrintable datasheet for anti-FGFR1OP (ARP53669_P050) antibody
Product Info
ReferenceMano,Y., (2007) Cancer Sci. 98 (12), 1902-1913
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human FGFR1OP
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 93%
Peptide SequenceSynthetic peptide located within the following region: FLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAEGTVGGPLLLE
Concentration0.5 mg/ml
Blocking PeptideFor anti-FGFR1OP (ARP53669_P050) antibody is Catalog # AAP53669 (Previous Catalog # AAPP30815)
Sample Type Confirmation

There is BioGPS gene expression data showing that FGFR1OP is expressed in HeLa

Gene SymbolFGFR1OP
Gene Full NameFGFR1 oncogene partner
Alias SymbolsFOP, FGFR1OP
NCBI Gene Id11116
Protein NameFGFR1 oncogene partner
Description of TargetFGFR1OP is a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t (6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage.This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.
Uniprot IDO95684
Protein Accession #NP_919410
Nucleotide Accession #NM_194429
Protein Size (# AA)379
Molecular Weight41kDa
Protein InteractionsCEP19; VASP; BRCA1; WRNIP1; ABL1; UBC; NAGK; FGFR1OP; CEP350; PACS1; PPP2R1A; PPP2R1B; PPP2CB; PPP2CA;
  1. What is the species homology for "FGFR1OP Antibody - N-terminal region (ARP53669_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "FGFR1OP Antibody - N-terminal region (ARP53669_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "FGFR1OP Antibody - N-terminal region (ARP53669_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "FGFR1OP Antibody - N-terminal region (ARP53669_P050)"?

    This target may also be called "FOP, FGFR1OP" in publications.

  5. What is the shipping cost for "FGFR1OP Antibody - N-terminal region (ARP53669_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "FGFR1OP Antibody - N-terminal region (ARP53669_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "FGFR1OP Antibody - N-terminal region (ARP53669_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "41kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "FGFR1OP Antibody - N-terminal region (ARP53669_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "FGFR1OP"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "FGFR1OP"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "FGFR1OP"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "FGFR1OP"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "FGFR1OP"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "FGFR1OP"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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