FGF22 Polyclonal Antibody (OABB00409)

Catalog No: OABB00409 (Formerly GWB-BBP332)

Size:100UG

Lane 1: Rat Ovary Tissue Lysate
Lane 2: Rat Ovary Tissue Lysate
Lane 3: Rat Testicle Tissue Lysate
Lane 4: Rat Testicle Tissue Lysate

Product Info

• Tested Species Reactivity: Human, Rat
• Predicted Species Reactivity: Hamster|Human|Mouse|Rat
• Product Format: Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Clonality: Polyclonal
• Clone: Polyclonal
• Isotype: Rabbit IgG
• Application: Western blot
• Additional Information: Notes: Tested Species: In-house tested species with positive results.
  Predicted Species: Species predicted to be fit for the product based on sequence similarities.
  Other applications have not been tested.
  Optimal dilutions should be determined by end users.
  
  Background: FGF22, Fibroblast growth factor 22, is a protein which in humans is encoded by the FGF22 gene. The FGF22 sequence in a genomic clone is assigned to 19p13.3. The protein encoded by this gene is a member of the fibroblast growth factor(FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. In situ hybridization demonstrated expression in the inner root sheath of the hair follicle. FGF22 is involved in hair development.
  Background: FGF22, Fibroblast growth factor 22, is a protein which in humans is encoded by the FGF22 gene. The FGF22 sequence in a genomic clone is assigned to 19p13.3. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. In situ hybridization demonstrated expression in the inner root sheath of the hair follicle. FGF22 is involved in hair development.
• Reconstitution and Storage: 2°C to 8°C|-20°C
• Immunogen: Polypeptide
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 500 ug/ml
• Specificity: No cross reactivity with other proteins.
• Application Info: Western blot: 0.1-0.5 ug/ml: Human, Rat: Mouse
• Reference: 1. Nakatake, Y., Hoshikawa, M., Asaki, T., Kassai, Y., Itoh, N.Identification of a novel fibroblast growth
  factor, FGF-22, preferentially expressed in the inner root sheath of the hair follicle.Biochim. Biophys.
  Acta 1517: 460-463, 2001.
  2. Terauchi, A., Johnson-Venkatesh, E. M., Toth, A. B., Javed, D., Sutton, M. A., Umemori, H.Distinct
  FGFs promote differentiation of excitatory and inhibitory synapses.Nature 465: 783-787, 2010.
  3. Umemori, H., Linhoff, M. W., Ornitz, D. M., Sanes, J. R. FGF22 and its close relatives are
  presynaptic organizing molecules in the mammalian brain.Cell 118: 257-270, 2004.
• Storage Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Description: Rabbit IgG polyclonal antibody for Fibroblast growth factor 22(FGF22) detection. Tested with WB in Human;Mouse;Rat.

Target Info

• Gene Symbol: FGF22
• Gene Full Name: fibroblast growth factor 22
• Alias Symbols: FGF-22;fibroblast growth factor 22.
• NCBI Gene Id: 27006
• Protein Name: Fibroblast growth factor 22
• Description of Target: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development.
• Uniprot ID: Q9HCT0
• Molecular Weight: 19663 MW