FES Recombinant Protein (OPCD03163)

Catalog No: OPCD03163

FES Recombinant Protein (OPCD03163) using SDS-PAGE

FES Recombinant Protein (OPCD03163) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Leu509-Asn766
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: FES
• Gene Full Name: FES proto-oncogene, tyrosine kinase
• Alias Symbols: feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog;feline sarcoma oncogene;feline sarcoma/Fujinami avian sarcoma oncogene homolog;FPS;Oncogene FES, feline sarcoma virus;p93c-fes;proto-oncogene c-Fes;proto-oncogene c-Fps;proto-oncogene tyrosine-protein kinase Fes/Fps;tyrosine-protein kinase Fes/Fps.
• NCBI Gene Id: 2242
• Protein Name: Tyrosine-protein kinase Fes/Fps
• Description of Target: Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28.
• Uniprot ID: P07332
• Protein Accession #: NP_001137255.1
• Nucleotide Accession #: NM_001143783.1
• Protein Size (# AA): Leu509~Asn766
• Molecular Weight: 33kDa