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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
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| Datasheets/Manuals | Printable datasheet for FES Antibody (OACA07144) (OACA07144) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Tyrosine-protein kinase Fes/Fps protein (120-420AA) |
| Purification | Affinity Purified |
| Preservative | 0.02% sodium azide |
| Formulation | PBS with, 50% glycerol, pH7.3. |
| Reference | [1]"Patterns of somatic mutation in human cancer genomes."Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C., Bignell G., Davies H., Teague J., Butler A., Stevens C., Edkins S., O'Meara S., Vastrik I., Schmidt E.E., Avis T., Barthorpe S., Bhamra G., Buck G. Stratton M.R.Nature 446:153-158(2007). [2]"Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation."Filippakopoulos P., Kofler M., Hantschel O., Gish G.D., Grebien F., Salah E., Neudecker P., Kay L.E., Turk B.E., Superti-Furga G., Pawson T., Knapp S. Cell 134:793-803(2008). [3]"Solution structure of the Src homology 2 domain from the human feline sarcoma oncogene Fes."Scott A., Pantoja-Uceda D., Koshiba S., Inoue M., Kigawa T., Terada T., Shirouzu M., Tanaka A., Sugano S., Yokoyama S., Guentert P.J. Biomol. NMR 31:357-361(2005). |
| Gene Symbol | FES |
|---|---|
| Gene Full Name | FES proto-oncogene, tyrosine kinase |
| Alias Symbols | feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog;feline sarcoma oncogene;feline sarcoma/Fujinami avian sarcoma oncogene homolog;FPS;Oncogene FES, feline sarcoma virus;p93c-fes;proto-oncogene c-Fes;proto-oncogene c-Fps;proto-oncogene tyrosine-protein kinase Fes/Fps;tyrosine-protein kinase Fes/Fps. |
| NCBI Gene Id | 2242 |
| Protein Name | Tyrosine-protein kinase Fes/Fps |
| Description of Target | Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28. |
| Uniprot ID | P07332 |
| Protein Accession # | NP_001137255 |
| Nucleotide Accession # | NM_001143783 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "FES Antibody (OACA07144)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "FES Antibody (OACA07144)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "FES Antibody (OACA07144)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "FES Antibody (OACA07144)"?
This target may also be called "feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog;feline sarcoma oncogene;feline sarcoma/Fujinami avian sarcoma oncogene homolog;FPS;Oncogene FES, feline sarcoma virus;p93c-fes;proto-oncogene c-Fes;proto-oncogene c-Fps;proto-oncogene tyrosine-protein kinase Fes/Fps;tyrosine-protein kinase Fes/Fps." in publications.
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What is the shipping cost for "FES Antibody (OACA07144)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "FES Antibody (OACA07144)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "FES Antibody (OACA07144)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "FES Antibody (OACA07144)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "FES"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "FES"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "FES"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "FES"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "FES"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "FES"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
