Ferritin Protein (OPPA01744)

Catalog No: OPPA01744 (Formerly GWB-B0F450)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid 20mM Tris-HCl pH 7.5
• Host: E. Coli
• Reconstitution and Storage: Store at 4C if entire vial will be used within 2-4 weeks.
  Store, frozen at -20C for longer periods of time.
  For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  Avoid multiple freeze-thaw cycles.
• Concentration: 1 mg/ml
• Purity: Greater than 90.0% as determined by SDS-PAGE.
• Peptide Sequence: MSSQIRQNYS TDVEAAVNSL VNLYLQASYT YLSLGFYFDR DDVALEGVSH FFRELAEEKR EGYERLLKMQ NQRGGRALFQ DIKKPAEDEW GKTPDAMKAA MALEKKLNQA LLDLHALGSA RTDPHLCDFL ETHFLDEEVK LIKKMGDHLT NLHRLGGPEA GLGEYLFERL TLKHD.

Target Info

• Gene Symbol: Ferritin Light
• Alias Symbols: LFTD, NBIA3
• NCBI Gene Id: 2512
• Protein Name: Ferritin light chain
• Description of Target: Ferritin is a fairly large, iron-storage heteropolymeric protein composed of 2 subunit types, light Ferritin & heavy Ferritin polypeptides, which is expressed in most kinds of cells and co-assemble in different proportion in a tissue-specific manner. Ferritin is composed of 24 self-assembled polypeptide subunits of the heavy and light ferritin chains and is characterized by the capacity to remove Fe from solution in the presence of oxygen. Ferritin light polypeptide protein is the main intracellular iron storage protein in prokaryotes and eukaryotes. Variation in ferritin subunit composition influence the rates of iron uptake and release in various tissues. A key function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyper ferrit anemia-cataract syndrome. Ferritin stores iron in a soluble, nontoxic, readily accessible form. Ferritin is needed for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after it has been oxidized.
  Ferritin Human Recombinant Light Chain produced in E.Coli is a single, non-glycosylated polypeptide chain containing 175 amino acids and having a molecular mass of 20 kDa.
• Uniprot ID: Q96AU9
• Protein Accession #: NP_000137.2
• Protein Size (# AA): Recombinant
• Molecular Weight: 20 kDa