FCN1 Recombinant Protein (OPCD03152)

Catalog No: OPCD03152

FCN1 Recombinant Protein (OPCD03152) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Lyophilized 20mM Tris, 150mM NaCl containing 0.01% SKL, 5% Trehalose
• Host: E.coli
• Conjugation: Unconjugated
• Application: Ctrl (+), SDS-PAGE, WB
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Arg25-Gly317
  Subcellular Location: Secreted
  Isoelectric Point: 6.3
• Reconstitution and Storage: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. Avoid repeated freeze/thaw cycles.
• Concentration: 80 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Fcna
• Gene Full Name: ficolin A
• Alias Symbols: collagen/fibrinogen domain-containing protein 1;Fcn;Fcn1;ficolin-1;Ficolin-A;ficolin-alpha;M-ficolin.
• NCBI Gene Id: 14133
• Protein Name: Ficolin-1
• Description of Target: Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage (By similarity).
• Uniprot ID: O70165
• Protein Accession #: NP_032021.1
• Nucleotide Accession #: NM_007995.3
• Protein Size (# AA): Arg25~Gly317
• Molecular Weight: 35kDa