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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OATA00256 |
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| Tested Species Reactivity | Human |
|---|---|
| Product Format | Liquid. 10 mM NaH2PO4, 150 mM NaCl, pH7.2 |
| Clonality | Monoclonal |
| Clone | 3G8 |
| Isotype | Mouse IgG1, k |
| Host | Mouse |
| Application | FC |
| Reconstitution and Storage | 2-8C |
| Specificity | CD16 |
| Application Info | Aviva tests all of our antibodies by flow cytometry. Citations may be provided as a resource for additional applications that have not been validated by Aviva - please consult Materials and Methods sections for additional details about the use of any product in these publications. |
| Reference | Fleit HB, Wright SD, Unkeless JC. 1982. Proc Natl Acad Sci U S A. May;79(10):3275-3279. Windebank KP, Abraham RT, Powis G, Olsen RA, Barna TJ, Leibson PJ. 1988. J Immunol. Dec 1;141(11):3951-3957. Fleit HB. 1991. Clin Immunol Immunopathol. May;59(2):222-235. Wirthmueller U, Kurosaki T, Murakami MS, Ravetch JV. 1992. J Exp Med. May 1;175(5):1381-1390. |
| Gene Symbol | FCGR3A, FCGR3B |
|---|---|
| Gene Full Name | Fc fragment of IgG receptor IIIa |
| Alias Symbols | CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR-10, FCRIII, FCGRIII, FCRIIIA |
| NCBI Gene Id | 2214; 2215 |
| Protein Name | low affinity immunoglobulin gamma Fc region receptor III-A |
| Description of Target | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P08637, O75015 |
| Protein Accession # | NP_000560.6 |
| Nucleotide Accession # | NM_000569.7 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "FCGR3A/FCGR3B Antibody (OATA00256)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "".
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How long will it take to receive "FCGR3A/FCGR3B Antibody (OATA00256)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "FCGR3A/FCGR3B Antibody (OATA00256)" provided in?
This item is provided in "Liquid. 10 mM NaH2PO4, 150 mM NaCl, pH7.2".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "FCGR3A/FCGR3B Antibody (OATA00256)"?
This target may also be called "CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR-10, FCRIII, FCGRIII, FCRIIIA" in publications.
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What is the shipping cost for "FCGR3A/FCGR3B Antibody (OATA00256)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "FCGR3A/FCGR3B Antibody (OATA00256)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "FCGR3A/FCGR3B Antibody (OATA00256)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "FCGR3A/FCGR3B Antibody (OATA00256)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "FCGR3A, FCGR3B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "FCGR3A, FCGR3B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "FCGR3A, FCGR3B"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "FCGR3A, FCGR3B"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "FCGR3A, FCGR3B"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "FCGR3A, FCGR3B"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
