FBXO2 Antibody (OAGA00359)

Catalog No: OAGA00359

Size:100 ul

Sample (30 ug of whole cell lysate)
A: H1299
12% SDS PAGE
OAGA00359 diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded Adrenal gland tumor, using FBXO2(OAGA00359) antibody at 1:100 dilution.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC-FFPE, WB
• Additional Information: Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. [provided by RefSeq]
  Positive Controls: A431, H1299, HepG2
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Synthetic peptide corresponding to a region within amino acids 234 and 296 of FBXO2 (Uniprot ID#Q9UK22)
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: FBXO2
• Gene Full Name: F-box only protein 2
• Alias Symbols: FBG1, FBX2, Fbs1, OCP1, NFB42
• NCBI Gene Id: 26232
• Protein Name: F-box only protein 2
• Uniprot ID: Q9UK22
• Protein Accession #: NP_036300.2
• Molecular Weight: 33 kDa