- Gene Symbol:
- FBP1
- NCBI Gene Id:
- 2203
- Official Gene Full Name:
- Fructose-1,6-bisphosphatase 1
- Protein Name:
- Fructose-1,6-bisphosphatase 1
- Swissprot Id:
- P09467
- Protein Accession #:
- NP_000498
- Nucleotide Accession #:
- NM_000507
- Alias Symbols:
- FBP
- Replacement Item:
- This antibody may replace item sc-121348, HPA005857
- Description of Target:
- Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
- Protein Size (# AA):
- 338
- Molecular Weight:
- 37kDa
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Purification:
- Protein A purified
- Application:
- IHC, WB
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express FBP1.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express FBP1.
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human FBP1
- Tested Species Reactivity:
- Human
- Predicted Homology Based on Immunogen Sequence:
- Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 86%; Zebrafish: 80%
- Complete computational species homology data:
- Anti-FBP1 (ARP41406_T100)
- Peptide Sequence:
- Synthetic peptide located within the following region: YVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAA
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
- Concentration:
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Protein Interactions:
- FBP2; FBP1; BIN1; KLRC2; ASL; UBC; POT1; TERF1; PARK2; HDAC6; PTK2; DYNC1I1; CSNK1E; BCL2L1; LNX1; PCNXL4; ATP5J2; ASCC2; RNF183; HSPA8; FXR2; ACTN1;
- Blocking Peptide:
- For anti-FBP1 (ARP41406_T100) antibody is Catalog # AAP41406 (Previous Catalog # AAPP24144)
- Datasheets/Manuals:
- Printable datasheet for anti-FBP1 (ARP41406_T100) antibody
- Additional Information:
- IHC Information: Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.
- Target Reference:
- Yanez,A.J., (2005) J. Cell. Physiol. 205 (1), 19-24
- Publications:
Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish 24465277
Product Reviews
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