FBL Recombinant Protein (OPCD00292)

Catalog No: OPCD00292

FBL Recombinant Protein (OPCD00292) using SDS-PAGE

FBL Recombinant Protein (OPCD00292) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Rat|Rattus norvegicus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gly85-Cys274
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Fbl
• Gene Full Name: fibrillarin
• Alias Symbols: histone-glutamine methyltransferase;nucleolar protein 1;rRNA 2'-O-methyltransferase fibrillarin;U6 snRNA 2'-O-methyltransferase fibrillarin.
• NCBI Gene Id: 292747
• Protein Name: rRNA 2'-O-methyltransferase fibrillarin
• Description of Target: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).
• Uniprot ID: P22509
• Protein Accession #: NP_001020814.1
• Nucleotide Accession #: NM_001025643.1
• Protein Size (# AA): Gly85~Cys274
• Molecular Weight: 25kDa