FAS Recombinant Protein (OPCD08009)

Catalog No: OPCD08009

FAS Recombinant Protein (OPCD08009) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Rat|Rattus norvegicus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 5% Trehalose.
• Host: 293F cell
• Conjugation: Unconjugated
• Application: Ctrl (+), SDS-PAGE, WB
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gln22-Leu171
  Subcellular Location: Membrane
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: 293-F Cells
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Fas
• Gene Full Name: Fas cell surface death receptor
• Alias Symbols: apo-1 antigen;apoptosis-mediating surface antigen FAS;CD95 antigen;Fas (TNF receptor superfamily, member 6);Fas antigen (ATP1);Fas receptor;FASLG receptor;Tnfrsf6;tumor necrosis factor receptor superfamily member 6;Tumor necrosis factor receptor superfamily, member 6.
• NCBI Gene Id: 246097
• Protein Name: Tumor necrosis factor receptor superfamily member 6
• Description of Target: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).
• Uniprot ID: Q63199
• Protein Accession #: NP_631933.2
• Nucleotide Accession #: NM_139194.2
• Protein Size (# AA): Gln22~Leu171
• Molecular Weight: 23/25kDa