FAM20A Antibody (OACD03385)

Catalog No: OACD03385

Western Blot with Human Recombinant Pseudokinase FAM20A

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid . 0.01M PBS, pH7.4, containing 0.05% Proclin300, 50% glycerol
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, ICC, IHC, IP
• Reconstitution and Storage: Store at 4°C for frequent use. Aliquot and store at -20°C for 24 months. Avoid repeated freeze/thaw cycles.
• Immunogen: Recombinant FAM20A (Lys368~Ser541) expressed in E.coli
• Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Concentration: 1 mg/ml
• Specificity: The antibody is a rabbit polyclonal antibody raised against FAM20A. It has been selected for its ability to recognize FAM20A in immunohistochemical staining and western blotting.
• Application Info: WB: 0.5-2ug/ml
  IHC: 5-20ug/ml
  ICC: 5-20ug/ml
  Optimal working dilutions must be determined by end user.
• Publications:

  Lack of FAM20A, Ectopic Gingival Mineralization and Chondro/Osteogenic Modifications in Enamel Renal Syndrome. Front Cell Dev Biol. 8, 605084 (2021). 33425910

  Pathogenesis of Enamel-Renal Syndrome Associated Gingival Fibromatosis: A Proteomic Approach. Front Endocrinol (Lausanne). 12, 752568 (2021). 34777248

Target Info

• Gene Symbol: FAM20A
• Gene Full Name: FAM20A, golgi associated secretory pathway pseudokinase
• Alias Symbols: AI1G, AIGFS, FP2747
• NCBI Gene Id: 54757
• Protein Name: Pseudokinase FAM20A
• Description of Target: Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals.
• Uniprot ID: Q96MK3
• Protein Accession #: NP_001230675.1
• Nucleotide Accession #: NM_001243746