Size:200ug
$219.00
Discontinued
SKU
APL10668
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F10 Protein Lysate (APL10668)

Catalog#: APL10668
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Reconstitution and StorageAdd 200ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Quality ControlThis product was tested on western blot.
Application : Western blot standard.
Observed Molecular Weight: 46
Expression system : Bacteria
TagGST in N-terminal
Datasheets/ManualsPrintable datasheet for anti-F10 (APL10668) antibody
Gene SymbolF10
Alias SymbolsFX, FXA
NCBI Gene Id2159
Protein NameCoagulation factor X
Description of TargetThis gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
Swissprot IdP00742
Protein Accession #NP_000495.1
Nucleotide Accession #NM_000504.3
Molecular Weight47
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express F10.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express F10.
Protein InteractionsUBC; GAD2; SERPINA10; HIST1H1C; MGST3; PRKAB1; SERPINA5; SERPINB8; F8; F10; F7; F5; PROS1; PLAT; PLG; SERPINB6; TFPI; APOH; GGCX; F3;
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