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F10 Protein Lysate (APL10668)

200ug
$219.00
In Stock
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Gene Symbol:
F10
Alias Symbols:
FX, FXA
NCBI Gene Id:
2159
Protein Name:
Coagulation factor X
Swissprot Id:
P00742
Protein Accession #:
NP_000495.1
Nucleotide Accession #:
NM_000504.3
Description of Target:
This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
Molecular Weight:
47
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express F10.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express F10.
Protein Interactions:
UBC; GAD2; SERPINA10; HIST1H1C; MGST3; PRKAB1; SERPINA5; SERPINB8; F8; F10; F7; F5; PROS1; PLAT; PLG; SERPINB6; TFPI; APOH; GGCX; F3;
Quality Control:
This product was tested on western blot.
Application : Western blot standard.
Observed Molecular Weight: 46
Expression system : Bacteria
Tag:
GST in N-terminal
Reconstitution and Storage:
Add 200ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Datasheets/Manuals:
Printable datasheet for anti-F10 (APL10668) antibody

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