EXOC3 Antibody (OAGA07065)

Catalog No: OAGA07065

Size:100 ul

Sample (30 ug of whole cell lysate)
A: HCT116
7.5% SDS PAGE
diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded mouse brain, using SEC6 antibody at 1:500 dilution.

SEC6 antibody detects SEC6 protein at cytosol on mouse middle brain by immunohistochemical analysis.
Sample: Paraffin-embedded mouse middle brain.
SEC6 antibody dilution: 1:500.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC-P, WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human SEC6. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 0.74 mg/ml
• Preservative: 0.01% Thimerosal
• Application Info: Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: EXOC3
• Gene Full Name: exocyst complex component 3
• Alias Symbols: SEC6, Sec6p, SEC6L1
• NCBI Gene Id: 11336
• Protein Name: exocyst complex component 3
• Description of Target: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
• Uniprot ID: O60645
• Protein Accession #: NP_009208.2
• Nucleotide Accession #: NM_007277.4