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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for anti-EXOC3 (OAED00238) antibody |
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Predicted Species Reactivity | Human, Mouse, Rat, Bovine, Dog, Chicken, Hamster, Monkey, Pig, Rabbit, Sheep |
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Clonality | Monoclonal |
Clone | 9H5 |
Isotype | IgG2a |
Host | Mouse |
Application | ICC, IHC, WB |
Reconstitution and Storage | Long Term Storage : -20C |
Immunogen | Recombinant rat Sec6. |
Specificity | Recognizes human, mouse, rat, bovine, dog, chicken, hamster, monkey, pig, rabbit and sheep rSec6. Detects a band of ~87kDa by Western blot. |
Formulation | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
Purity | Protein G affinity purified. |
Application Info | Immunocytochemistry Immunohistochemistry (paraffin sections) Western Blot (1:250, ECL) Optimal conditions must be determined individually for each application. |
Reference | Large-scale quantitative LC-MS/MS analysis of detergent-resistant membrane proteins from rat renal collecting duct: M. Knepper, et al. ; Am. J. Physiol., Cell Physiol. 295, C661 (2008), Application(s): WB using rat tissue, Abstract; Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells: E. Rodriguez-Boulan, et al. ; Nat. Cell Biol. 5, 126 (2003), Application(s): ICC using canine samples, Abstract; The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene: P.J. Robinson, et al. ; J. Biol. Chem. 276, 29792 (2001), Application(s): WB using rat samples, Abstract; |
Gene Symbol | EXOC3 |
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Gene Full Name | Exocyst complex component 3 |
Alias Symbols | SEC6, Sec6p, SEC6L1 |
NCBI Gene Id | 11336 |
Protein Name | Exocyst complex component 3 |
Description of Target | rSec6 and rSec8 are rat homologs of the yeast Sec6 and Sec8 proteins that are essential for protein transport between the Golgi apparatus and the plasma membrane. In yeast, Sec8 is part of a 19.5S complex that includes Sec6 and Sec15, that also associate with the ras-like GTP binding protein Sec4. An analogous 17S complex in rat brain was found to contain rSec6 and rSec8, along with eight proteins with a combined molecular weight of 743 kDa. The membrane-associated rSec6/8 complex co-immunoprecipitates with syntaxin, providing evidence that this complex is involved in synaptic vesicle docking and fusion at the presynaptic terminal. |
Uniprot ID | O60645 |
Protein Accession # | NP_009208.2 |
Nucleotide Accession # | NM_007277.4 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "EXOC3 Antibody (OAED00238)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Bovine, Dog, Chicken, Hamster, Monkey, Pig, Rabbit, Sheep".
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How long will it take to receive "EXOC3 Antibody (OAED00238)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 week".
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What buffer format is "EXOC3 Antibody (OAED00238)" provided in?
This item is provided in "".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "EXOC3 Antibody (OAED00238)"?
This target may also be called "SEC6, Sec6p, SEC6L1" in publications.
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What is the shipping cost for "EXOC3 Antibody (OAED00238)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "EXOC3 Antibody (OAED00238)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "EXOC3 Antibody (OAED00238)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "EXOC3 Antibody (OAED00238)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "EXOC3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "EXOC3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "EXOC3"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "EXOC3"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "EXOC3"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "EXOC3"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.