EVER2 Antibody (OAPB00679)

Catalog No: OAPB00679

Size:100UG

Western blot analysis of EVER2 in Jurkat cell lysate with EVER2 antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry of EVER2 in human brain with EVER2 antibody at 5 ug/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. EVER2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: EVER2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: EVER2 antibody was raised against a 14 amino acid synthetic peptide from near the center of human EVER2. The immunogen is located within amino acids 300 - 350 of EVER2.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-EVER2 antibody is Catalog # OEPB02795
• Application Info: EVER2 antibody can be used for detection of EVER2 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Ramoz N, Taieb A, Rueda L-A, et al. Evidence for a nonallelic heterogeneity of epidermodysplasia verruciformis with two susceptibility loci mapped to chromosome regions 2p21-p24 and 17q25. J. Invest. Dermatol.2000; 114:1148-53.;Ramoz N, Rueda L-A, Bouadjar B, et al. Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis. Nat. Genet.2002; 32:579-81.;Lazarczyk M, Pons C, Mendoza J-A, et al. Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses. J. Exp. Med.2008; 205:35-42.;

Target Info

• Gene Symbol: TMC8
• Gene Full Name: transmembrane channel like 8
• Alias Symbols: epidermodysplasia verruciformis 2;epidermodysplasia verruciformis protein 2;EV2;EVER2;EVIN2;transmembrane channel-like protein 8.
• NCBI Gene Id: 147138
• Protein Name: large EVER2 protein [Homo sapiens]|Transmembrane channel-like protein 8
• Description of Target: Probable ion channel.
• Uniprot ID: Q8IU68
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/AAM44454