ETV4 Antibody (OAEC04418)

Catalog No: OAEC04418

Size:100 ug/100 ul

Western blot analysis using ETV4 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY ETV4 cDNA (2).

Western blot analysis using ETV4 mouse mAb against K562 cell lysate (1).

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid.Ascitic fluid containing 0.03% sodium azide.
• Clonality: Monoclonal
• Clone: 1A2G3
• Isotype: IgG1
• Host: Mouse
• Application: WB, ELISA
• Reconstitution and Storage: Store at 4C, for long term storage, store at -20C.
• Immunogen: Purified recombinant fragment of human ETV4 (aa50-109) expressed in E. Coli.
• Concentration: 1 ug/ul
• Application Info: WB1/500 - 1/2000
  ELISA: 1/10000

Target Info

• Gene Symbol: ETV4
• Gene Full Name: ets variant 4
• Alias Symbols: E1AF, PEA3, E1A-F, PEAS3
• NCBI Gene Id: 2118
• Description of Target: ETV4. ets variant gene 4 (E1Aenhancer binding protein, E1AF), also known as PEA3. Several members of the Ets gene family are known to encode sequencespecific DNA binding proteins. These include mouse PU.1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2 and rat GABP-alpha. Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element. For instance, PEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), but does not bind to the sequence 5'-AGGAAC-3', recognized by PU.1, although PU.1 binds equally well to both sequences. It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells. This is in contrast to other members of the Ets gene family, such as Ets-1, Ets-2 and Fli-1, each of which is expressed primarily in cells of hematopoietic origin.
• Uniprot ID: P43268
• Molecular Weight: 54 kDa