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ESR1 Antibody (OADC00047)

50ug
$319.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. Provided in PBS containing 0.01% thimerosal; purified by ammonium sulphate precipitation followed by dialysis.
Clonality:
Monoclonal
Isotype:
IgG3
Host:
Mouse
Conjugation:
Unconjugated
Application:
CHIP, WB, IHC
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-102391 from Santa Cruz Biotechnology.
Purification:
Protein A/G purified
Concentration:
2 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-ESR1 (OADC00047) antibody
Preservative:
0.01% Thimerosal
Specificity:
Mouse monoclonal antibody raised against HDAC1
Application Info:
CHIP: 5 ug/CHIP
Western Blotting: 7 ug/ml
Immunochemistry 15 ug/ml
Gene Symbol:
ESR1
Official Gene Full Name:
estrogen receptor 1
Alias Symbols:
ER, ESR, Era, ESRA, ESTRR, NR3A1
NCBI Gene Id:
2099;
Protein Name:
estrogen receptor
Description of Target:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
Swissprot Id:
P03372
Protein Accession #:
NP_000116.2
Nucleotide Accession #:
NM_000125.3
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ESR1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ESR1.

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