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Predicted Species ReactivityHuman
Product FormatLiquid. Provided in PBS containing 0.01% thimerosal; purified by ammonium sulphate precipitation followed by dialysis.
ApplicationCHIP, WB, IHC
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
Replacement ItemThis antibody may replace item sc-102391 from Santa Cruz Biotechnology.
PurificationProtein A/G purified
Concentration2 mg/mL
Datasheets/ManualsPrintable datasheet for anti-ESR1 (OADC00047) antibody
Preservative0.01% Thimerosal
SpecificityMouse monoclonal antibody raised against HDAC1
Application InfoCHIP: 5 ug/CHIP
Western Blotting: 7 ug/ml
Immunochemistry 15 ug/ml
Gene SymbolESR1
Official Gene Full Nameestrogen receptor 1
Alias SymbolsER, ESR, Era, ESRA, ESTRR, NR3A1
NCBI Gene Id2099;
Protein Nameestrogen receptor
Description of TargetThis gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
Swissprot IdP03372
Protein Accession #NP_000116.2
Nucleotide Accession #NM_000125.3
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express ESR1.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express ESR1.
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