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ESR1 Antibody (OADC00046)

100ul
$319.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. Ascites fluid from mouse containing 0.05% azide.
Clonality:
Monoclonal
Isotype:
IgG1 kappa
Host:
Mouse
Conjugation:
Unconjugated
Application:
WB, GS, IHC, IP, CHIP
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-102391 from Santa Cruz Biotechnology.
Purification:
Ascites fluid
Predicted Homology Based on Immunogen Sequence:
Mouse
Concentration:
Undetermined, ascites
Datasheets/Manuals:
Printable datasheet for anti-ESR1 (OADC00046) antibody
Preservative:
0.05% Sodium Azide
Specificity:
Monoclonal antibody raised in mouse against human ERalpha (estrogen receptor alpha), using a synthetic peptide.
Application Info:
ELISA: 1:500 -1:5,000
Western Blotting: 1:500 -1:5,000
Gel Supershift 1:10 - 1:20
Immunochemistry 1:500 -1:5,000
Immunoprecipitation: 1:200 -1:5,000
CHIP: 2.5 ul/CHIP
Gene Symbol:
ESR1
Official Gene Full Name:
estrogen receptor 1
Alias Symbols:
ER, ESR, Era, ESRA, ESTRR, NR3A1
NCBI Gene Id:
2099;
Protein Name:
estrogen receptor
Description of Target:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
Swissprot Id:
P03372
Protein Accession #:
NP_000116.2
Nucleotide Accession #:
NM_000125.3
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ESR1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ESR1.

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