ESR1 Antibody (OADC00046)
|Predicted Species Reactivity||Human|
|Product Format||Liquid. Ascites fluid from mouse containing 0.05% azide.|
|Application||WB, GS, IHC, IP, CHIP|
|Reconstitution and Storage||Store at -20C. Avoid repeated freeze/thaw cycles.|
|Replacement Item||This antibody may replace item sc-102391 from Santa Cruz Biotechnology.|
|Predicted Homology Based on Immunogen Sequence||Mouse|
|Datasheets/Manuals||Printable datasheet for anti-ESR1 (OADC00046) antibody|
|Preservative||0.05% Sodium Azide|
|Specificity||Monoclonal antibody raised in mouse against human ERalpha (estrogen receptor alpha), using a synthetic peptide.|
|Application Info||ELISA: 1:500 -1:5,000
Western Blotting: 1:500 -1:5,000
Gel Supershift 1:10 - 1:20
Immunochemistry 1:500 -1:5,000
Immunoprecipitation: 1:200 -1:5,000
CHIP: 2.5 ul/CHIP
|Official Gene Full Name||estrogen receptor 1|
|Alias Symbols||ER, ESR, Era, ESRA, ESTRR, NR3A1|
|NCBI Gene Id||2099;|
|Protein Name||estrogen receptor|
|Description of Target||This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.|
|Protein Accession #||NP_000116.2|
|Nucleotide Accession #||NM_000125.3|
|Tissue Tool||Find tissues and cell lines supported by DNA array analysis to express ESR1.|
|RNA Seq||Find tissues and cell lines supported by RNA-seq analysis to express ESR1.|
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
What is the species homology for "ESR1 Antibody (OADC00046)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
How long will it take to receive "ESR1 Antibody (OADC00046)"?
What buffer format is "ESR1 Antibody (OADC00046)" provided in?
This item is provided in "Liquid. Ascites fluid from mouse containing 0.05% azide.".
Additional format options may be available. For more information please contact email@example.com.
What are other names for "ESR1 Antibody (OADC00046)"?
This target may also be called "ER, ESR, Era, ESRA, ESTRR, NR3A1" in publications.
What is the shipping cost for "ESR1 Antibody (OADC00046)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
What is the guarantee for "ESR1 Antibody (OADC00046)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "ESR1 Antibody (OADC00046)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "ESR1 Antibody (OADC00046)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.
What are positive controls for "ESR1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "ESR1"?
What other proteins interact with "ESR1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "ESR1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "ESR1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "ESR1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.