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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for ERN2 Antibody (OAAF02511) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid |
Clonality | Polyclonal |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Paraffin |
Reconstitution and Storage | -20°C |
Immunogen | The antiserum was produced against synthesized peptide derived from human ERN2. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Specificity | ERN2 antibody detects endogenous levels of total ERN2 protein. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Dilution | The optimal working dilution should be determined by the end user. |
Application Info | IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:10000 |
Reference | Iwawaki T., Nat. Cell Biol. 3:158-164(2001). Ota T., Nat. Genet. 36:40-45(2004). |
Gene Symbol | ERN2 |
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Gene Full Name | endoplasmic reticulum to nucleus signaling 2 |
Alias Symbols | endoplasmic reticulum to nucleus signalling 2;Endoplasmic reticulum-to-nucleus signaling 2;ER to nucleus signalling 2;hIRE2p;inositol-requiring 1 beta;inositol-requiring protein 2;IRE1 beta;IRE1, S. cerevisiae, homolog of;IRE1b;IRE1-BETA;IRE2p;serine/threonine-protein kinase/endoribonuclease IRE2. |
NCBI Gene Id | 10595 |
Protein Name | Serine/threonine-protein kinase/endoribonuclease IRE2 |
Description of Target | Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins. |
Uniprot ID | Q76MJ5 |
Protein Accession # | NP_150296.3 |
Molecular Weight | 102 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ERN2 Antibody (OAAF02511)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "ERN2 Antibody (OAAF02511)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "ERN2 Antibody (OAAF02511)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ERN2 Antibody (OAAF02511)"?
This target may also be called "endoplasmic reticulum to nucleus signalling 2;Endoplasmic reticulum-to-nucleus signaling 2;ER to nucleus signalling 2;hIRE2p;inositol-requiring 1 beta;inositol-requiring protein 2;IRE1 beta;IRE1, S. cerevisiae, homolog of;IRE1b;IRE1-BETA;IRE2p;serine/threonine-protein kinase/endoribonuclease IRE2." in publications.
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What is the shipping cost for "ERN2 Antibody (OAAF02511)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ERN2 Antibody (OAAF02511)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ERN2 Antibody (OAAF02511)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "102 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ERN2 Antibody (OAAF02511)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ERN2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ERN2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ERN2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ERN2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ERN2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ERN2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.