Loading...
Catalog No: OAAB16895
Size:400ul
Price: $396.00
SKU
OAAB16895
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for OAAB16895
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationWB
::Cellular Location: Endoplasmic reticulum membrane; Single-pass type I membrane protein
Reconstitution and StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis ERN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-810 amino acids from the C-terminal region of human ERN2.
PurificationThis antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Predicted Homology Based on Immunogen SequenceHuman
ConcentrationVaries by lot. See vial for concentration.
Application InfoWB: 1:1000
Gene SymbolERN2
Alias SymbolsIRE1b, IRE2p, hIRE2p, IRE1-BETA
NCBI Gene Id10595
Protein NameSerine/threonine-protein kinase/endoribonuclease IRE2
Description of TargetERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
Uniprot IDQ76MJ5
Protein Accession #NP_150296.3
Molecular Weight102 kDa
  1. What is the species homology for "ERN2 Antibody - C-terminal region (OAAB16895)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "ERN2 Antibody - C-terminal region (OAAB16895)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks ".

  3. What buffer format is "ERN2 Antibody - C-terminal region (OAAB16895)" provided in?

    This item is provided in "Liquid PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ERN2 Antibody - C-terminal region (OAAB16895)"?

    This target may also be called "IRE1b, IRE2p, hIRE2p, IRE1-BETA" in publications.

  5. What is the shipping cost for "ERN2 Antibody - C-terminal region (OAAB16895)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ERN2 Antibody - C-terminal region (OAAB16895)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ERN2 Antibody - C-terminal region (OAAB16895)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "102 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ERN2 Antibody - C-terminal region (OAAB16895)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ERN2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ERN2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ERN2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ERN2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ERN2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ERN2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:ERN2 Antibody - C-terminal region (OAAB16895)
Your Rating
We found other products you might like!