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Datasheets/Manuals | Printable datasheet for anti-ERBB4 (OAAJ02732) antibody |
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Predicted Species Reactivity | Human, Mouse, Rat |
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Product Format | Liquid PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | WB, IHC, IF, ICC |
Additional Information | Subcellular Location: Membrane and Nucleus. Following proteolytical processing E4ICD (E4ICD1 or E4ICD2 generated from the respective isoforms) is translocated to the nucleus. Significantly more E4ICD2 than E4ICD1 is found in the nucleus. E4ICD2 colocalizes with YAP1 in the nucleus. Tissue Specificity: Expressed at highest levels in brain, heart, kidney, in addition to skeletal muscle, parathyroid, cerebellum, pituitary, spleen, testis and breast. Lower levels in thymus, lung, salivary gland, and pancreas. Isoform JM-A CYT-1 and isoform JM-B CYT-1 are expressed in cerebellum, but only the isoform JM-B is expressed in the heart. |
Reconstitution and Storage | Store at -20°C. Stable for 12 months from date of receipt. |
Immunogen | A synthesized peptide derived from human HER4 around the phosphorylation site of Tyrosine 1284 |
Purification | The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. |
Concentration | 1 mg/ml |
Specificity | Phospho-HER4 (Tyr1284) antibody detects endogenous levels of HER4 only when phosphorylated at Tyrosine 1284 |
Application Info | WB: 1:500~2000 IHC: 1:50~200 IF/ICC: 1:100~500 P-ELISA: 1:20000~40000 |
Gene Symbol | ERBB4 |
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Gene Full Name | erb-b2 receptor tyrosine kinase 4 |
Alias Symbols | HER4, ALS19, p180erbB4 |
NCBI Gene Id | 2066 |
Description of Target | The HER4/ERBB4 gene is a member of the type I receptor tyrosine kinase subfamily that includes EGFR (MIM 131550), ERBB2 (MIM 164870), and ERBB3 (MIM 190151). It encodes a receptor for NDF/heregulin (MIM 142445). |
Uniprot ID | Q15303 |
Molecular Weight | 180 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ERBB4 Antibody (Phospho-Tyr1284) (OAAJ02732)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
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How long will it take to receive "ERBB4 Antibody (Phospho-Tyr1284) (OAAJ02732)"?
This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".
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What buffer format is "ERBB4 Antibody (Phospho-Tyr1284) (OAAJ02732)" provided in?
This item is provided in "Liquid PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ERBB4 Antibody (Phospho-Tyr1284) (OAAJ02732)"?
This target may also be called "HER4, ALS19, p180erbB4" in publications.
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What is the shipping cost for "ERBB4 Antibody (Phospho-Tyr1284) (OAAJ02732)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ERBB4 Antibody (Phospho-Tyr1284) (OAAJ02732)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ERBB4 Antibody (Phospho-Tyr1284) (OAAJ02732)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "180 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ERBB4 Antibody (Phospho-Tyr1284) (OAAJ02732)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ERBB4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ERBB4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ERBB4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ERBB4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ERBB4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ERBB4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.