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Catalog No: OPCD02954
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OPCD02954
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Datasheets/ManualsPrintable datasheet for EPOR Recombinant Protein (OPCD02954)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Arg276-Ala496
::Subcellular Location: Cell membrane;Single-pass type I membrane protei
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His and GST Tag
Gene SymbolEPOR
Gene Full Nameerythropoietin receptor
Alias SymbolsEPO-R;erythropoietin receptor;truncated erythropoietin receptor.
NCBI Gene Id2057
Protein NameErythropoietin receptor
Description of TargetReceptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Uniprot IDP19235
Protein Accession #NP_000112.1
Nucleotide Accession #NM_000121.3
Protein Size (# AA)Arg276~Ala496
Molecular Weight54kDa
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