EPHB1 Antibody (Phospho-Tyr594/604) (OASG02495)

Catalog No: OASG02495

Size:100 uL

Western Blot using HeLa

Western Blot using HeLa, A431

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human EphB1/2 around the phosphorylation site of Y594/604. Location: 530-610aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Tyr594/604
• Specificity: Phospho-EphB1/2 (Tyr594/604) Polyclonal Antibody detects endogenous levels of EphB1/2 protein only when phosphorylated at Y594/604.
• Application Info: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000;

Target Info

• Gene Symbol: EPHA2, EPHB1
• Gene Full Name: EPH receptor B1
• Alias Symbols: ELK, NET, Hek6, EPHT2
• NCBI Gene Id: 2047; 1969; 270190; 24338
• Description of Target: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
• Uniprot ID: P54762, P29323, Q8CBF3, P54763, P09759
• Molecular Weight: 110 kDa