Catalog No: OACA09207
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OACA09207
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Datasheets/ManualsPrintable datasheet for EPHB1 Antibody (OACA09207) (OACA09207)
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunohistochemistry
Reconstitution and Storage-20°C or -80°C
ImmunogenRecombinant Human Ephrin type-B receptor 1 protein (260-500AA)
PurificationAffinity Purified
Preservative0.02% sodium azide
FormulationPBS with, 50% glycerol, pH7.3.
Gene SymbolEPHB1
Gene Full NameEPH receptor B1
Alias SymbolsEK6;ELK;eph tyrosine kinase 2;EPH-like kinase 6;ephrin type-B receptor 1;EPHT2;Hek6;NET;neuronally-expressed EPH-related tyrosine kinase;soluble EPHB1 variant 1;tyrosine-protein kinase receptor EPH-2.
NCBI Gene Id2047
Protein NameEphrin type-B receptor 1
Description of TargetReceptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively. Involved in the maintenance of the pool of satellite cells (muscle stem cells) by promoting their self-renewal and reducing their activation and differentiation (By similarity).
Uniprot IDP54762
Protein Accession #NP_004432
Nucleotide Accession #NM_004441
  1. What is the species homology for "EPHB1 Antibody (OACA09207)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "EPHB1 Antibody (OACA09207)"?

    This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".

  3. What buffer format is "EPHB1 Antibody (OACA09207)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "EPHB1 Antibody (OACA09207)"?

    This target may also be called "EK6;ELK;eph tyrosine kinase 2;EPH-like kinase 6;ephrin type-B receptor 1;EPHT2;Hek6;NET;neuronally-expressed EPH-related tyrosine kinase;soluble EPHB1 variant 1;tyrosine-protein kinase receptor EPH-2." in publications.

  5. What is the shipping cost for "EPHB1 Antibody (OACA09207)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "EPHB1 Antibody (OACA09207)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "EPHB1 Antibody (OACA09207)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "EPHB1 Antibody (OACA09207)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "EPHB1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "EPHB1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "EPHB1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "EPHB1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "EPHB1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "EPHB1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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