EPHA3 Antibody (Phospho-Tyr779/833) (OASG02487)

Catalog No: OASG02487

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human EphA3/4/5 around the phosphorylation site of Y779/833. Location: 720-800aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Tyr779/833
• Specificity: Phospho-EphA3/4/5 (Tyr779/833) Polyclonal Antibody detects endogenous levels of EphA3/4/5 protein only when phosphorylated at Y779/833.
• Application Info: IHC 1:100-1:300; ELISA 1:10000;

Target Info

• Gene Symbol: EPHA3, EPHA4, EPHA5
• Gene Full Name: EPH receptor A3
• Alias Symbols: EK4, ETK, HEK, ETK1, HEK4, TYRO4
• NCBI Gene Id: 2042; 2043; 13838; 13839; 29210; 79208
• Description of Target: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.
• Uniprot ID: P29320, P54764, P54756, P29319, Q03137, Q60629, O08680, P54757
• Molecular Weight: 110 kDa