ENTPD2 Antibody - N-terminal region (OAAB19520)

Catalog No: OAAB19520

Size:100ul

Western blot analysis of lysate from mouse heart tissue lysate, using ENTPD2 Antibody (N-term) (OAAB19520). OAAB19520 was diluted at 1: 1000. A goat anti-rabbit IgG H&L (HRP) at 1: 10000 dilution was used as the secondary antibody.Lysate at 20ug.

Product Info

• Product Format: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Application Info: WB: 1:1000
• Reference: Chadwick B.P.,et al.Mamm. Genome 8:668-672(1997).
  Mateo J.,et al.Br. J. Pharmacol. 128:396-402(1999).
  Mukasa T.,et al.Biochemistry 44:11160-11170(2005).
  Humphray S.J.,et al.Nature 429:369-374(2004).
  Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
  

Target Info

• Gene Symbol: ENTPD2
• Alias Symbols: CD39L1, NTPDase-2
• NCBI Gene Id: 954
• Description of Target: CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. CD39L1 is a 495 amino acid multi-pass membrane protein that requires calcium and magnesium cofactors to hydrolyze ATP and other nucleotides in the regulation of purigenic neurotransmission. CD39L1 is expressed in kidney, colon, heart, testis, pancreas, brain, prostate, skeletal muscle, small intestine and ovaries. There are two isoforms of CD39L1 that are produced as a result of alternative splicing events.
• Uniprot ID: Q9Y5L3
• Molecular Weight: 54 kDa