Catalog No: OPCD02926
Price: $0.00
SKU
OPCD02926
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
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Datasheets/Manuals | Printable datasheet for ENPP1 Recombinant Protein (OPCD02926) |
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Predicted Species Reactivity | Rat|Rattus norvegicus |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Glu568-Ile793 |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 95% |
Source | E.coli |
Tag | N-terminal His and GST Tag |
Gene Symbol | Enpp1 |
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Gene Full Name | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
Alias Symbols | ectonucleotide pyrophosphatase/phosphodiesterase family member 1;E-NPP 1;Npps;Pc1;phosphodiesterase I/nucleotide pyrophosphatase 1;plasma-cell membrane glycoprotein PC-1. |
NCBI Gene Id | 85496 |
Protein Name | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
Description of Target | By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity. |
Uniprot ID | Q924C3 |
Protein Accession # | NP_445987.1 |
Nucleotide Accession # | NM_053535.1 |
Protein Size (# AA) | Glu568~Ile793 |
Molecular Weight | 60kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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