ENPP1 Recombinant Protein (OPCD02925)

Catalog No: OPCD02925

ENPP1 Recombinant Protein (OPCD02925) using SDS-PAGE

ENPP1 Recombinant Protein (OPCD02925) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Asp362-Trp518
  Subcellular Location: Membrane; Single-pass type II membrane protein. Basolateral cell membrane; Single-pass type II membrane protei
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: ENPP1
• Gene Full Name: ectonucleotide pyrophosphatase/phosphodiesterase 1
• Alias Symbols: alkaline phosphodiesterase 1;ARHR2;COLED;ectonucleotide pyrophosphatase/phosphodiesterase family member 1;E-NPP 1;Ly-41 antigen;M6S1;Membrane component chromosome 6 surface marker 1;membrane component, chromosome 6, surface marker 1;NPP1;NPPS;PC-1;PCA1;PDNP1;phosphodiesterase I/nucleotide pyrophosphatase 1;plasma-cell membrane glycoprotein 1;plasma-cell membrane glycoprotein PC-1.
• NCBI Gene Id: 5167
• Protein Name: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
• Description of Target: By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.
• Uniprot ID: P22413
• Protein Accession #: NP_006199.2
• Nucleotide Accession #: NM_006208.2
• Protein Size (# AA): Asp362~Trp518
• Molecular Weight: 20kDa