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WRNIP1 antibody - N-terminal region (ARP36470_P050)

100 ul

Regular Price: $289.00

Special Price: $215.00

In Stock

Conjugation Options

ARP36470_P050-FITC Conjugated

ARP36470_P050-HRP Conjugated

ARP36470_P050-Biotin Conjugated

Gene Symbol:
WRNIP1
NCBI Gene Id:
56897
Official Gene Full Name:
Werner helicase interacting protein 1
Protein Name:
ATPase WRNIP1
Swissprot Id:
Q96S55
Protein Accession #:
NP_569079
Nucleotide Accession #:
NM_130395
Alias Symbols:
FLJ22526, RP11-420G6.2, WHIP, bA420G6.2
Replacement Item:
This antibody may replace item sc-55437 from Santa Cruz Biotechnology.
Description of Target:
Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.
Protein Size (# AA):
640
Molecular Weight:
72kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express WRNIP1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express WRNIP1.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human WRNIP1
Species Reactivity:
Cow, Dog, Human, Mouse, Pig, Rat, Yeast, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Cow: 79%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 79%; Rat: 100%; Yeast: 77%; Zebrafish: 85%
Complete computational species homology data:
Anti-WRNIP1 (ARP36470_P050)
Peptide Sequence:
Synthetic peptide located within the following region: PGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPT
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; RNF31; PIN1; ELP2; ELP3; TRIM28; HDAC11; EPAS1; VCP; SRSF4; SMAD2; RAD18; NUP107; WRNIP1; FGFR1OP; POLD1; ABL1; SUMO2; TOLLIP; DDX58; USP11; OSBPL10; USP25; POLD4; POLD2; WRN;
Blocking Peptide:
For anti-WRNIP1 (ARP36470_P050) antibody is Catalog # AAP36470 (Previous Catalog # AAPP08529)
Datasheets/Manuals:
Printable datasheet for anti-WRNIP1 (ARP36470_P050) antibody
Target Reference:
Tsurimoto,T., et al., (2005) Genes Cells 10 (1), 13-22

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