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TRPA1 Recombinant Protein (OPCD07720)

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10ug
    $145.00
    In Stock
    Gene Symbol:
    TRPA1
    Official Gene Full Name:
    transient receptor potential cation channel subfamily A member 1
    NCBI Gene Id:
    8989
    Alias Symbols:
    ANKTM1, Ankyrin-like with transmembrane domains protein 1, Transformation-sensitive protein p120, Transient receptor potential cation channel subfamily A member 1
    Description of Target:
    Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function . Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, cinnamaldehyde, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes . Is also activated by menthol (in vitro). Acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana . May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system.
    Swissprot Id:
    O75762
    Protein Accession #:
    NP_015628.2
    Nucleotide Accession #:
    NM_007332.2
    Host:
    E.coli
    Conjugation:
    Unconjugated
    Protein Name:
    Transient receptor potential cation channel subfamily A member 1
    Molecular Weight:
    38 kDa
    Tissue Tool:
    Find tissues and cell lines supported by DNA array analysis to express TRPA1.
    RNA Seq:
    Find tissues and cell lines supported by RNA-seq analysis to express TRPA1.
    Product Format:
    Lyophilized
    Species Reactivity:
    Human
    Formulation:
    Lyophilized in PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
    Purity:
    > 90%
    Source:
    Prokaryotic Expressed Recombinant
    Application:
    SDS-PAGE, WB, ELISA, IP
    Additional Information:
    Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
    :::
    Residues: Asp63 - Ile370
    Tag:
    N-terminal His Tag
    Reconstitution and Storage:
    Reconstitute in PBS or others.
    Store at 2-8C for one month. Aliquot and store at -80C for 12 months. Avoid repeated freeze/thaw cycles.
    Datasheets/Manuals:
    Printable datasheet for OPCD07720
    Protocol:
    Tips Information:
     
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