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TP53 Antibody - N-terminal region (OAGA01350)

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100 ul
$289.00
In Stock
Gene Symbol:
TP53
NCBI Gene Id:
7157
Official Gene Full Name:
tumor protein p53
Swissprot Id:
P04637
Alias Symbols:
P53, BCC7, LFS1, TRP53
Replacement Item:
This antibody may replace item sc-126 from Santa Cruz Biotechnology.
Description of Target:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Purified by antigen-affinity chromatography.
Application:
IF, IHC-P, IP, WB
Tissue Tool:
Find tissues and cell lines supported to express TP53.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TP53.
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human p53. The exact sequence is proprietary.
Species Reactivity:
Human
Product Format:
Liquid. 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Concentration:
1mg/ml
Datasheets / Downloads:
Printable datasheet for anti-TP53 (OAGA01350) antibody
Isotype:
IgG
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000, ICC/IF: 1:100-1:1000, IP: 1:100-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Protocol:
Tips Information:
 
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