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TBX3 antibody - middle region (ARP33411_P050)

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100 ul

Regular Price: $289.00

Special Price: $215.00

In Stock

Conjugation Options

ARP33411_P050-FITC Conjugated

ARP33411_P050-HRP Conjugated

ARP33411_P050-Biotin Conjugated

Gene Symbol:
TBX3
NCBI Gene Id:
6926
Official Gene Full Name:
T-box 3
Protein Name:
T-box transcription factor TBX3
Swissprot Id:
O15119
Protein Accession #:
NP_057653
Nucleotide Accession #:
NM_016569
Alias Symbols:
TBX3-ISO, UMS, XHL
Replacement Item:
This antibody may replace item sc-166623 from Santa Cruz Biotechnology.
Description of Target:
TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.
Protein Size (# AA):
743
Molecular Weight:
79kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TBX3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TBX3.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human TBX3
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 100%; Rat: 92%
Complete computational species homology data:
Anti-TBX3 (ARP33411_P050)
Peptide Sequence:
Synthetic peptide located within the following region: VGTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGS
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
CA8; AES; SOX2; Dlg4; ELAVL1; HDAC5; HDAC3; HDAC2; HDAC1; TOLLIP; TBX3;
Blocking Peptide:
For anti-TBX3 (ARP33411_P050) antibody is Catalog # AAP33411 (Previous Catalog # AAPP04457)
Datasheets/Manuals:
Printable datasheet for anti-TBX3 (ARP33411_P050) antibody
Target Reference:
Yarosh,W., (2008) Cancer Res. 68 (3), 693-699
 
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