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SOX2 Antibody (OAGA01620)

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100 ul
$289.00
In Stock
Gene Symbol:
SOX2
NCBI Gene Id:
6657
Official Gene Full Name:
SRY (sex determining region Y)-box 2
Swissprot Id:
P48431
Alias Symbols:
ANOP3, MCOPS3
Replacement Item:
This antibody may replace item sc-17319 from Santa Cruz Biotechnology.
Description of Target:
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Purified by antigen-affinity chromatography.
Application:
FACS, IF, IHC-P, IP, WB
Tissue Tool:
Find tissues and cell lines supported to express SOX2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SOX2.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human SOX2. The exact sequence is proprietary.
Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Concentration:
1mg/ml
Datasheets / Downloads:
Printable datasheet for anti-SOX2 (OAGA01620) antibody
Isotype:
IgG
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:20000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)], ICC/IF: 1:50-1:500, FACS: 1:50-1:200, IP: 1:100-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
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Protocol:
Tips Information:
 
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