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SNCA Antibody (OAAN02180)

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Gene Symbol:
SNCA
NCBI Gene Id:
6622
Official Gene Full Name:
synuclein alpha
Protein Name:
Alpha-synuclein
Swissprot Id:
P37840
Protein Accession #:
NP_000336.1
Nucleotide Accession #:
NM_000345.3
Alias Symbols:
PD1, NACP, PARK1, PARK4, PD1, NACP, PARK1, PARK4, synuclein alpha, Alpha-synuclein, SNCA
Description of Target:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Molecular Weight:
14 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified against immunogen
Application:
WB, IHC, IF
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SNCA.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SNCA.
Immunogen:
Recombinant protein of human SNCA
Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Datasheets/Manuals:
Printable datasheet for anti-SNCA (OAAN02180)
Preservative:
0.02% Sodium Azide
Conjugation:
Unconjugated
Isotype:
IgG
Application Info:
WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200. IF: 1:50 - 1:100
Storage Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Protocol:
Tips Information:

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