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SNCA Antibody (OAAD00426)

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0.1 mg
$335.00
In Stock
Gene Symbol:
SNCA
NCBI Gene Id:
6622
Protein Name:
Alpha-synuclein
Swissprot Id:
P37840
Alias Symbols:
PD1, NACP, PARK1, PARK4,
Replacement Item:
This antibody may replace item sc-10717 from Santa Cruz Biotechnology.
Description of Target:
Alpha-synuclein (SNCA), with 140-amino acid pro- tein (about 15kDa), belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentra- tions in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body dis- ease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer’s disease. Immunohis- tochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson’s disease, Dementia with Lewy bodies and Multiple System Atrophy.
Host:
Mouse
Clonality:
Monoclonal
Application:
WB, IHC, ELISA
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SNCA.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SNCA.
Species Reactivity:
Human
Datasheets / Downloads:
Printable datasheet for SNCA Antibody (OAAD00426) - OAAD00426
Formulation:
Crude ascites.
Clone:
2B2D1, 2B2A11
Application Info:
Western Blot: 1: 500- 1: 2, 000 IHC(P): 1: 500- 1: 2, 000 IHC(F): 1: 500- 1: 2, 000 ELISA: Propose dilution 1: 10, 000 Determining optimal working dilutions by titration test.*
Target Reference:
1. J. Johnson, S. M. Hague, M. Hanson Neurology, Aug 2004; 63: 554 - 556 2. Hong Tao Li, Xiao Jing Lin, Yuan Yuan Xie Protein Pept Lett. 2006;13(4):385-90.
Protocol:
Tips Information:
 
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