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SIRT6 antibody - N-terminal region (ARP32409_T100)

100 ul

Regular Price: $229.00

Special Price: $215.00

In Stock

Conjugation Options

ARP32409_T100-FITC Conjugated

ARP32409_T100-HRP Conjugated

ARP32409_T100-Biotin Conjugated

Gene Symbol:
SIRT6
NCBI Gene Id:
51548
Official Gene Full Name:
Sirtuin 6
Protein Name:
NAD-dependent protein deacetylase sirtuin-6
Swissprot Id:
Q8N6T7
Protein Accession #:
NP_057623
Nucleotide Accession #:
NM_016539
Alias Symbols:
SIR2L6
Replacement Item:
This antibody may replace item sc-517196 from Santa Cruz Biotechnology.
Description of Target:
SIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by SIRT6 is included in class IV of the sirtuin family.
Protein Size (# AA):
355
Molecular Weight:
39kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SIRT6.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SIRT6.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT6
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 92%; Dog: 100%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Complete computational species homology data:
Anti-SIRT6 (ARP32409_T100)
Peptide Sequence:
Synthetic peptide located within the following region: STASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVG
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; MDM2; AKT1; STUB1; SKP2; ABCF2; FAF1; VIM; UBE2D1; CHD3; NR0B2; tat; CCNDBP1; RELA; XRCC5; PRKDC; XRCC6; ELF5;
Blocking Peptide:
For anti-SIRT6 (ARP32409_T100) antibody is Catalog # AAP32409 (Previous Catalog # AAPP03404)
Datasheets/Manuals:
Printable datasheet for anti-SIRT6 (ARP32409_T100) antibody
Target Reference:
Frye,R.A., (2000) Biochem Biophys Res Commun. 273(2), 793-8

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